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Effect of using peptide as a replacement of antibiotic growth promoters on pigs: a systematic review and meta-regression.

Adli, D. N. and Sholikin, M. M. and Qomariyah, N. and Prihambodo, T. R. and Sjofjan, O. and Hidayat, C. and Sadarman, S. and Nurfitriani, R. A. and Jayanegara, A. and Solfaine, R. and Nahrowi, N.

Journal of Advanced Veterinary Research (2022) 12: 29–35

Link: https://advetresearch.com/index.php/AVR/article/view/831

Abstract

A systematic review and meta-regression were done to investigate the effect of using peptide as a replacement of antibiotic growth promoters on pig. A dataset was created based on an algorithm for peer-reviewed articles published from 2004 to 2019. The peer-reviewed published articles were evaluated strictly following the eligibility criteria for inclusion. Meta-regression was performed using a nonlinear mixed model library provided by R Studio 4.1.1 software. A structure algorithm was constructed using ’magick’, ’ggplot’, ’ggplot2’ and ’cowplot’ add-ons to create a meta-regression. In this study, metaregression between year of publication and number of pigs included in the experiments was associated with growth performance and diarrhea with p = 0.032 and p \textless 0.163, respectively. Meanwhile, the source of peptide intercepts for these parameters were 38.33 (p = 0.052) and 48.44 (p = \textless 0.071), respectively. The scientific evidence from the meta-analysis based on the in-vivo studies demonstrates that both form and dosage of the anti-microbial have a beneficial effect on pigs.

Citation

Adli, D. N., Sholikin, M. M., Qomariyah, N., Prihambodo, T. R., Sjofjan, O., Hidayat, C., Sadarman, S., Nurfitriani, R. A., Jayanegara, A., Solfaine, R., & Nahrowi, N. (2022). Effect of using peptide as a replacement of antibiotic growth promoters on pigs: a systematic review and meta-regression. Journal of Advanced Veterinary Research, 12(1), 29–35. https://advetresearch.com/index.php/AVR/article/view/831 Swine, meta-analysis, systematic reviews, diarrhoea, growth rate, regression analysis, antibiotics, growth promoters, Anti-Bacterial Agents, algorithms, antidiarrhoeal properties, C-Peptide, medicated feeds

Keywords