Probiotics in animal husbandry: applicability and associated risk factors

Alayande, K. A. and Aiyegoro, O. A. and Ateba, C. N.

Sustainability (2020) 12:

DOI: 10.3390/su12031087

Abstract

Probiotics have been emerging as a safe and viable alternative to antibiotics for increasing performance in livestock. Literature was collated via retrieved information from online databases, viz, PubMed, MEDLINE, ScienceDirect, Scopus, Web of Science and Google Scholar. Besides improved immunomodulation and nutrient digestibility, in-feed probiotics have shown drastic reductions in gastrointestinal tract-invading pathogens. However, every novel probiotic strain cannot be assumed to share historical safety with conventional strains. Any strain not belonging to the wild-type distributions of relevant antimicrobials, or found to be harbouring virulence determinants, should not be developed further. Modes of identification and the transmigration potential of the strains across the gastrointestinal barrier must be scrutinized. Other potential risk factors include the possibility of promoting deleterious metabolic effects, excessive immune stimulation and genetic stability of the strains over time. Adverse effects of probiotics could be strain specific, depending on the prevailing immunological and physiological condition of the host. The most crucial concern is the stability of the strain. Probiotics stand a good chance of replacing antibiotics in animal husbandry. The possibility of the probiotics used in animal feed cross-contaminating the human food chain cannot be downplayed. Thus, the established safety measures in probiotic development must be adhered to for a successful global campaign on food safety and security.

Citation

Alayande, K. A., Aiyegoro, O. A., & Ateba, C. N. (2020). Probiotics in animal husbandry: applicability and associated risk factors. Sustainability, 12(3). https://doi.org/10.3390/su12031087 immune system, Animal Immunology [LL650], Host Resistance and Immunity [HH600], Animal Nutrition (Production Responses) [LL520], Animal Nutrition (Physiology) [LL510], diets, domestic animals, livestock, risk factors, feed additives, digestibility, pathogens, immunity, animal feeding, strains, probiotics, Fermentation Technology and Industrial Microbiology [WW500], Feed Additives [RR130], Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821], Biochemistry and Physiology of Microorganisms [ZZ394]

Keywords

• immune system
• Animal Immunology [LL650]
• Host Resistance and Immunity [HH600]
• Animal Nutrition (Production Responses) [LL520]
• Animal Nutrition (Physiology) [LL510]
• diets
• domestic animals
• livestock
• risk factors
• feed additives
• digestibility
• pathogens
• immunity
• animal feeding
• strains
• probiotics
• Fermentation Technology and Industrial Microbiology [WW500]
• Feed Additives [RR130]
• Prion
• Viral
• Bacterial and Fungal Pathogens of Animals [LL821]
• Biochemistry and Physiology of Microorganisms [ZZ394]