VetSRev
Database of veterinary systematic reviews
Database of veterinary systematic reviews
Comprehensive Reviews in Food Science and Food Safety (2020) 19: 1488–1520
Due to the digestible refractory and absorbable structures of bioactive peptides (BPs), they could induce notable biological impacts on the living organism. In this regard, the current study was devoted to providing an overview regarding the available methods for BPs generation by the aid of a systematic review conducted on the published articles up to April 2019. In this context, the PubMed and Scopus databases were screened to retrieve the related publications. According to the results, although the characterization of BPs mainly has been performed using enzymatic and microbial in-vitro methods, they cannot be considered as suitable techniques for further stimulation of digestion in the gastrointestinal tract. Therefore, new approaches for both in-vivo and in-silico methods for BPs identification should be developed to overcome the obstacles that belonged to the current methods. The purpose of this review was to compile the recent analytical methods applied for studying various aspects of food-derived biopeptides, and emphasizing generation at in vitro, in vivo, and in silico.
Barati, M., Javanmardi, F., Jazayeri, S. M. H. M., Jabbari, M., Rahmani, J., Barati, F., Nickho, H., Davoodi, S. H., Roshanravan, N., & Khaneghah, A. M. (2020). Techniques, perspectives, and challenges of bioactive peptide generation: a comprehensive systematic review. Comprehensive Reviews in Food Science and Food Safety, 19(4), 1488–1520. https://doi.org/10.1111/1541-4337.12578 animal models, Techniques and Methodology [ZZ900], man, systematic reviews, in vitro, Information and Documentation [CC300], Animal and in vitro Models for Pharmaceuticals [VV450], Animal Models of Human Diseases [VV400], peptides, bioactivity, biological activity, analytical methods, analytical techniques, computer simulation