Systematization of the prevalence of Anaplasma spp. in canines and meta-analysis of A. platys and A. phagocytophilum. [Spanish]

Cardona Arias, J. A. and Zapata Marin, J. and Uran Velasquez, J. M.

Revista MVZ Cordoba (2019) 24: 7239–7247

DOI: https://doi.org/10.21897/rmvz.1310

Abstract

Objective. To estimate the general prevalence of Anaplasma spp. and specific prevalence of A. platys and A. phagocytophilum in canines, through studies published between 2000 and 2018. Material and methods. Systematic review with 14 search strategies, guaranteeing completeness and reproducibility according PRISMA. Quality was evaluated with STROBE. The global prevalence and the specific ones were estimated according to country, period and diagnostic test, with their confidence intervals of 95%. Forest Plot was performed for the individual and global prevalence of A platys or A. phagocytophilum according to PCR, ELISA and IFI, which were compared based on Statistic Z. Results. Thirty studies were included with 18 472 canines, mostly from Brazil, United States and Germany. In IFI the prevalence was 39.0% (95% CI=37.0-41.0), in ELISA 9.3% (95% CI=8.8-9.8) and in CRP 7.1% (95% CI=6.4-7.8). The prevalence based on CRP was statistically greater in America with 11.9% (95% CI=10.5-13.3) compared to 5.5% in Africa (95% CI=1.2-9.7), Asia 4.1% (95% CI=3.1-5.1) and Europe 3.5% (95% CI=2.5-4.5). The prevalence of A. platys with CRP was 16.1% (IC95%=14.2-17.9) and of A. phagocytophilum 3.7% (95% CI=2.8-4.6). Conclusions. A high prevalence of global infection was found, with greater importance of A. platys, in a low number of publications worldwide and with a high heterogeneity according to the country, the diagnostic technique and the species involved.

Citation

Cardona Arias, J. A., Zapata Marin, J., & Uran Velasquez, J. M. (2019). Systematization of the prevalence of Anaplasma spp. in canines and meta-analysis of A. platys and A. phagocytophilum. [Spanish]. Revista MVZ Cordoba, 24(2), 7239–7247. https://doi.org/https://doi.org/10.21897/rmvz.1310 dogs, meta-analysis, Brazil, Europe, Germany, disease prevalence, epidemiology, Africa, bacterial diseases, Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821], Anaplasma, Anaplasma infections, Anaplasma phagocytophilum, anaplasmoses, rickettsial diseases, United States of America, USA, Anaplasma platys

Keywords

• dogs
• meta-analysis
• Brazil
• Europe
• Germany
• disease prevalence
• epidemiology
• Africa
• bacterial diseases
• Prion
• Viral
• Bacterial and Fungal Pathogens of Animals [LL821]
• Anaplasma
• Anaplasma infections
• Anaplasma phagocytophilum
• anaplasmoses
• rickettsial diseases
• United States of America
• USA
• Anaplasma platys