VetSRev
Database of veterinary systematic reviews
Database of veterinary systematic reviews
J Anim Physiol Anim Nutr (Berl) (2021) 105: 442–451
DOI: 10.1111/jpn.13479
The objective was to conduct a systematic review to evaluate the effects of dietary supplementation with beta-adrenergic agonists on calpains and calpastatin activity in bovine muscle and changes in meat tenderness. A survey was conducted in June 2019 on Science Direct, Web of Science, Scopus, PubMed and Capes Periodicals, using four keyword combinations: agonist and calpain and cattle; agonist and calpain and bovine; agonist and calpain and heifers; agonist and calpain and steers. Thirteen studies were selected, 54% concluded that supplementation with beta-adrenergic agonists increases calpastatin activity, 23% observed increase in their gene expression and 23% reported no effect on activity or expression of this enzyme. Nine studies evaluated the influence of beta-adrenergic agonists supplementation on meat texture and all found an increase in shear force values. There is strong evidence that beta-adrenergic agonists may increase calpastatin activity in the muscle, causing damage to meat tenderness.
Cruz, F. L., de Carvalho, E. B., Ramos, E. M., Pereira, L. J., & Zangeronimo, M. G. (2021). Relationship between beta-adrenergic agonists, calpain system activity and beef texture: A systematic review. J Anim Physiol Anim Nutr (Berl), 105(3), 442–451. https://doi.org/10.1111/jpn.13479 Animals, Female, Proteolysis, Cattle, Meat, beef cattle, enzymes, Muscle, Skeletal/metabolism, Muscles/metabolism, *Adrenergic beta-Agonists/metabolism/pharmacology, *Calpain/metabolism, meat tenderization, muscle proteolysis, zipaterol