The skeletal effects of tanshinones: a review

Ekeuku, S. O. and Pang, KokLun and Chin, KokYong

Molecules (2021) 26:

DOI: 10.3390/molecules26082319

Abstract

Background: Osteoporosis results from excessive bone resorption and reduced bone formation, triggered by sex hormone deficiency, oxidative stress and inflammation. Tanshinones are a class of lipophilic phenanthrene compounds found in the roots of Salvia miltiorrhiza with antioxidant and anti-inflammatory activities, which contribute to its anti-osteoporosis effects. This systematic review aims to provide an overview of the skeletal beneficial effects of tanshinones.

Citation

Ekeuku, S. O., Pang, K. L., & Chin, K. Y. (2021). The skeletal effects of tanshinones: a review. Molecules, 26(8). https://doi.org/10.3390/molecules26082319 apoptosis, animal models, man, systematic reviews, plants, medicinal plants, plant extracts, antiinflammatory properties, antioxidant properties, bone diseases, bones, clinical trials, Animal and in vitro Models for Pharmaceuticals [VV450], Animal Models of Human Diseases [VV400], drug plants, medicinal herbs, officinal plants, Non-food/Non-feed Plant Products [SS200], anti-inflammatory properties, anti-oxidant properties, cell culture, bone destruction, bone resorption, radical scavenging properties, Salvia miltiorrhiza, bone calcification, bone formation

Keywords

• apoptosis
• animal models
• man
• systematic reviews
• plants
• medicinal plants
• plant extracts
• antiinflammatory properties
• antioxidant properties
• bone diseases
• bones
• clinical trials
• Animal and in vitro Models for Pharmaceuticals [VV450]
• Animal Models of Human Diseases [VV400]
• drug plants
• medicinal herbs
• officinal plants
• Non-food/Non-feed Plant Products [SS200]
• anti-inflammatory properties
• anti-oxidant properties
• cell culture
• bone destruction
• bone resorption
• radical scavenging properties
• Salvia miltiorrhiza
• bone calcification
• bone formation