Evidence related to the use of ancillary drugs in bovine respiratory disease (anti-inflammatory and others): are they justified or not?

Francoz, D and Buczinski, S and Apley, M

Veterinary Clinics of North America. Food Animal Practice (2012) 28: 23–38, vii

DOI: 10.1016/j.cvfa.2011.12.003

Abstract

The therapeutic approach for bovine respiratory disease (BRD) includes antimicrobial treatment due to the frequent implication of bacteria. The data concerning the use of ancillary drugs (such as anti-inflammatory drugs or immunomodulators) are scant and often are based on experimental models of BRD. The effect of NSAIDs on pulmonary lesions, despite appearing beneficial, remains to be confirmed in well-designed, long-term trials. The impact on weight gain is inconsistent in these studies. This review emphasized the need for articles concerning clinical trials to clearly state study inclusion criteria, and definitions of clinical scores, relapses, and treatment failures to be properly evaluated.

Citation

Francoz, D., Buczinski, S., & Apley, M. (2012). Evidence related to the use of ancillary drugs in bovine respiratory disease (anti-inflammatory and others): are they justified or not? Veterinary Clinics of North America. Food Animal Practice, 28(1), 23–38, vii. https://doi.org/10.1016/j.cvfa.2011.12.003 Animals, Treatment Outcome, Cattle, Anti-Inflammatory Agents, Evidence-Based Medicine, Anti-Bacterial Agents/therapeutic use, Cattle Diseases/drug therapy, Non-Steroidal/therapeutic use, Bovine Respiratory Disease Complex/drug therapy, Immunomodulation

Keywords

• Animals
• Treatment Outcome
• Cattle
• Anti-Inflammatory Agents
• Evidence-Based Medicine
• Anti-Bacterial Agents/therapeutic use
• Cattle Diseases/drug therapy
• Non-Steroidal/therapeutic use
• Bovine Respiratory Disease Complex/drug therapy
• Immunomodulation