VetSRev
Database of veterinary systematic reviews
Database of veterinary systematic reviews
Chinese Journal of Animal Nutrition (2022) 34: 3317–3328
DOI: 10.3969/j.issn.1006-267x.2022.05.057
In order to explore the effects of probiotics on intestinal barrier function of weaned piglets, this study conducted a Meta-analysis of relevant studies. Randomized controlled trials on the effects of probiotics supplementation on intestinal health of weaned piglets were searched by searching CNKI, Weipu, Science Direct and Web of Science databases. The retrieval period was from database construction to April 2021. The inclusion and exclusion criteria of samples were set for literature screening and data extraction. A total of 720 samples were included. R language was used for correlation analysis of the included studies, and standardized mean difference (SMD) was selected as the effect index. Meta-analysis results showed that the addition of probiotics in weaned piglets could effectively alleviate diarrhea compared with the blank control group[P \textless 0.01, SMD=-15.15, 95% confidence interval (CI):-21.55 to -8.76] and increase the expression level of zonula occludens protein-1 (ZO-1) (P \textless 0.01, SMD=20.83, 95% CI:8.84 to 32.83), Occludin (P \textless 0.01, SMD=2.587, 95% CI:0.67 to 4.50), promote the growth of jejunum villi (P \textless 0.01, SMD=15.22, 95% CI:5.91 to 24.54). The results indicate that probiotics can protect the intestinal barrier function of weaned piglets.
Gao JingChun, Cao ShuTing, Jiang ZongYong, & Wang Li. (2022). Meta analysis of effects of probiotics on intestinal barrier function of weaned piglets. Chinese Journal of Animal Nutrition, 34(5), 3317–3328. https://doi.org/10.3969/j.issn.1006-267x.2022.05.057 meta-analysis, data analysis, research, intestines, correlation analysis, diarrhoea, feed supplements, weaning, databases, screening, randomized controlled trials, barriers, probiotics, Probiotics, piglets, jejunum, villi