Bromelain and its therapeutic applications in the human gastrointestinal system: a scoping review.

Gonzalez Taracena, M. and Valencia Ruiz, K. I. and Martinez Baez, A. Z. and Marquez Zamora, L. and Ramirez Lopez, E.

Aplicaciones terapeuticas de la bromelina en el sistema gastrointestinal en humanos: una revision de alcance. (2022) 21: 39–49

DOI: 10.29105/respyn21.2-5

Abstract

Introduction: Bromelain has been used for therapeutic purposes since the 19th century. Different studies have been reported both in vitro experimentation and in animals and even in humans that showed favorable results for the gastrointestinal system. Background:To develop a review of the investigations carried out in the last two decades that refer to the gastrointestinal therapeutic use of bromelain in humans, animals and in vitro experimentation. Material and method: An exploratory review (scoping review) was carried out based on the PRISMA requirements for this type of review. The documentary search was carried out in the studies published in the PubMed, ScienceDirect, Scopus, Google Scholar, Springer Link and Wiley databases. Results:Thirteen articles were found, five clinical trials, four in animals and four in vitro. The results of the therapeutic effects of bromelain were significant due to its properties as an analgesic, antacid, anticancer, anti-inflammatory, immunomodulatory, prebiotic, probiotic, in reducing constipation and gastric emptying. Conclusions: Bromelain has beneficial effects at the gastrointestinal level in humans, it is only necessary to deepen the evidence to continue the research of the last two decades.

Citation

Gonzalez Taracena, M., Valencia Ruiz, K. I., Martinez Baez, A. Z., Marquez Zamora, L., & Ramirez Lopez, E. (2022). Bromelain and its therapeutic applications in the human gastrointestinal system: a scoping review. Aplicaciones Terapeuticas De La Bromelina En El Sistema Gastrointestinal En Humanos: Una Revision De Alcance., 21(2), 39–49. https://doi.org/10.29105/respyn21.2-5 Humans, reviews, animal models, systematic reviews, in vitro, human diseases, antiinflammatory properties, immunomodulatory properties, probiotics, gastrointestinal diseases, biological activity, antineoplastic properties, analgesic properties, stomach, Humanism, Humanities, antacids, Bromelains, constipation, human experimentation, stomach emptying

Keywords

• Humans
• reviews
• animal models
• systematic reviews
• in vitro
• human diseases
• antiinflammatory properties
• immunomodulatory properties
• probiotics
• gastrointestinal diseases
• biological activity
• antineoplastic properties
• analgesic properties
• stomach
• Humanism
• Humanities
• antacids
• Bromelains
• constipation
• human experimentation
• stomach emptying