Is there a place for dexmedetomidine in equine anaesthesia and analgesia? A systematic review (2005-2017)

Gozalo-Marcilla, M. and Gasthuys, F. and Luna, S. P. L. and Schauvliege, S.

J Vet Pharmacol Ther (2018) 41: 205–217

DOI: 10.1111/jvp.12474

Abstract

The objective of this review was to perform a literature compilation of all the equine publications that used dexmedetomidine as the first article on this topic was published, in 2005. We also aimed to answer the question whether the use of dexmedetomidine can currently be justified. For that, we compiled information from databases, such as PubMed, Google Scholar and Web of Science and the proceedings of the last veterinary anaesthesiology meetings. Dexmedetomidine is an attractive drug to be used in horses, mainly due to its pharmacokinetic profile and pharmacodynamics that favour its use as intravenous constant rate infusion (CRI). Nowadays, its clinical use is popular for sedation in prolonged standing procedures and during partial intravenous anaesthesia (PIVA) and total intravenous anaesthesia (TIVA). However, legal requirements for its use should be taken into account.

Citation

Gozalo-Marcilla, M., Gasthuys, F., Luna, S. P. L., & Schauvliege, S. (2018). Is there a place for dexmedetomidine in equine anaesthesia and analgesia? A systematic review (2005-2017). J Vet Pharmacol Ther, 41(2), 205–217. https://doi.org/10.1111/jvp.12474 Animals, *Horses, Analgesia/methods/*veterinary, Anesthesia/methods/*veterinary, Dexmedetomidine/*therapeutic use, Hypnotics and Sedatives/*therapeutic use

Keywords

• Animals
• *Horses
• Analgesia/methods/*veterinary
• Anesthesia/methods/*veterinary
• Dexmedetomidine/*therapeutic use
• Hypnotics and Sedatives/*therapeutic use