The effects of heat stress exposure on free amino acid concentrations within the plasma and the brain of heat-exposed chicks: A systematic review and meta-analysis

Jafari, M. J. and Iranpour, S. and Gravandi, S. and Tehrani, B. J. and Askari, M. and Omidi, A. and Nasori, M.

J Therm Biol (2021) 97: 102872

DOI: 10.1016/j.jtherbio.2021.102872

Abstract

This study was conducted in order to investigate the effects of heat stress exposure on the concentrations of amino acids within the plasma and the brain of chicks. Methodology: Five electronic databases including; PubMed, Scopus, Web of Science, Embase and ProQuest were reviewed to find relative literature published until the March 8, 2019. A total of eight relative studies and 194 chicks were analyzed. The Random Effects model and the Fixed Effects model were performed. Using the Random Effects model for amino acids, a Standardized mean difference (SMD) of 2.05 and 1.46 was obtained for alanine and threonine concentrations respectively. This indicates a significant increase in the concentration of these amino acids within the plasma. An SMD of -2.68 and -2.46 was obtained for cysteine and proline concentrations respectively, this indicates a significant decrease in the concentration of these amino acids within the plasma. The pooled estimates regarding the effect of heat stress exposure on plasma amino acid concentrations for proline were -0.013. The SMDs obtained for amino acid concentrations within the brain (diencephalon) including leucine, methionine, valine and isoleucine were 1.799, 0.88, 2.11, 1.85, respectively, This indicates a significant increase in the concentration of these amino acids within the brain (P \textless 0.05). Comparing the SMD obtained for long-term heat exposure (two weeks) with the SMD obtained for short-term heat exposure shows that plasma amino acid concentrations including aspartic acid, glutamic acid, leucine, lysine, methionine, valine, isoleucine, tyrosine, glycine, proline, phenylalanine and threonine had all decreased. The relationship between heat exposure and changes in the concentration of some amino acids in the plasma is an important scientific finding.

Citation

Jafari, M. J., Iranpour, S., Gravandi, S., Tehrani, B. J., Askari, M., Omidi, A., & Nasori, M. (2021). The effects of heat stress exposure on free amino acid concentrations within the plasma and the brain of heat-exposed chicks: A systematic review and meta-analysis. J Therm Biol, 97, 102872. https://doi.org/10.1016/j.jtherbio.2021.102872 Heat stress, Plasma, Amino acids, Brain, Chicks

Keywords

• Heat stress
• Plasma
• Amino acids
• Brain
• Chicks