VetSRev
Database of veterinary systematic reviews
Database of veterinary systematic reviews
Neuroscience and biobehavioral reviews (2023) 144: 105001
DOI: 10.1016/j.neubiorev.2022.105001
This systematic review and meta-analysis (PROSPERO registration animal/human studies: CRD42021234793/CRD42021234790) examined the relationship between sleep and appetitive conditioning. Inclusion criteria included: a) appetitive conditioning paradigm; b) measure of conditioning; c) sleep measurement and/or sleep loss; d) human and/etor non-human animal samples; and e) written in English. Searches of seven databases returned 3777 publications. The final sample consisted of 42 studies using primarily animal samples and involving food- and drug-related conditioning tasks. We found sleep loss disrupted appetitive conditioning of food rewards (p \textless 0.001) but potentiated appetitive conditioning of drug rewards (p \textless 0.001). Furthermore, sleep loss negatively impacted extinction learning irrespective of the reward type. Post-learning sleep was associated with increases in REM sleep (p = 0.02). Findings suggest sleep loss potentiates the impact of psychoactive substances in a manner likely to produce an increased risk of problematic substance use. In obese/overweight populations, sleep loss may be associated with deficits in the conditioning and extinction of reward-related behaviours. Further research should assess the relationship between sleep and appetitive conditioning in humans.
Kavaliotis E, Boardman JM, Clark JW, Ogeil RP, Verdejo-García A, & Drummond SPA. (2023). The relationship between sleep and appetitive conditioning: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews, 144, 105001. https://doi.org/10.1016/j.neubiorev.2022.105001 Animals, Humans, Obesity, Reward, Sleep, *Conditioning, Classical, *Learning, Appetite, Appetitive Behavior, Overweight