Therapeutic efficiency of antibiotics and prostaglandin F2alpha in postpartum dairy cows with clinical endometritis: an evidence-based evaluation

Lefebvre, R C and Stock, A E

Veterinary Clinics of North America. Food Animal Practice (2012) 28: 79–96, ix

DOI: 10.1016/j.cvfa.2012.01.002

Abstract

The occurrence of vaginal discharge in postpartum dairy cows is generally diagnosed as clinical endometritis. This uterine condition is associated with reduced fertility and economic loss for the dairy industry. Therapeutic approaches include the systemic or intrauterine application of antibiotics or the injection of prostaglandin F2alpha and analogues to cause luteolysis and uterine contractions to evacuate the infected content. The treatment of clinical endometritis remains a subject of considerable controversy in the literature. Better understanding of the reproductive biology of normal versus abnormal uterine involution and immune mechanisms will allow more efficient diagnostic methods and a more efficient therapeutic approach.

Citation

Lefebvre, R. C., & Stock, A. E. (2012). Therapeutic efficiency of antibiotics and prostaglandin F2alpha in postpartum dairy cows with clinical endometritis: an evidence-based evaluation. Veterinary Clinics of North America. Food Animal Practice, 28(1), 79–96, ix. https://doi.org/10.1016/j.cvfa.2012.01.002 Animals, Female, Pregnancy, Treatment Outcome, Cattle, Evidence-Based Medicine, Anti-Bacterial Agents/therapeutic use, Cattle Diseases/drug therapy, Dinoprost/therapeutic use, Endometritis/drug therapy/veterinary, Postpartum Period

Keywords

• Animals
• Female
• Pregnancy
• Treatment Outcome
• Cattle
• Evidence-Based Medicine
• Anti-Bacterial Agents/therapeutic use
• Cattle Diseases/drug therapy
• Dinoprost/therapeutic use
• Endometritis/drug therapy/veterinary
• Postpartum Period