VetSRev
Database of veterinary systematic reviews
Database of veterinary systematic reviews
Toxicon (2021) 195: 78–85
DOI: 10.1016/j.toxicon.2021.03.010
Mimosa tenuiflora (Willd.) Poir. (Fabaceae) is a plant native to Brazil and occurs in the phytogeographic domains of Caatinga and Cerrado. Relevant studies have investigated the chemical components of this plant and others have already demonstrated its teratogenic potential. It has been proven that this plant causes congenital malformations in farm animals and, consequently, financial losses to farmers in the Brazilian semiarid region. The present work aimed to carry out a bibliographic survey on the teratogenic effects of M. tenuiflora in ruminants and to group the chemical compounds occurring in this species. For this, databases were consulted and twenty-four articles published in the last 30 years (1990-2020) were included. According to the scientific documents analyzed, M. tenuiflora has embryotoxic, fetotoxic and abortive potential in farm animals, especially sheep and goats. The main classes of chemical compounds present in this species are alkaloids, saponins, flavonoids, and terpenoids. It is likely that some of these substances, mainly the indole alkaloid N,N-dimethyltryptamine, are related to the teratogenic effects reported in ruminants in the Brazilian semiarid region.
Lima Bezerra, J. J., Vieira Pinheiro, A. A., & Barbosa Lucena, R. (2021). Phytochemistry and teratogenic potential of Mimosa tenuiflora (willd.) poir. (Fabaceae) in ruminants: A systematic review. Toxicon, 195, 78–85. https://doi.org/10.1016/j.toxicon.2021.03.010 Animals, Sheep, Brazil, Ruminants, *Fabaceae, Toxic plant, *Mimosa, Brazilian semiarid region, Chemical compounds, Embryotoxic, Plant Poisoning/*veterinary, Production animals, Teratogens/*toxicity