VetSRev
Database of veterinary systematic reviews
Database of veterinary systematic reviews
Microbial Pathogenesis (2021) 150: 150
DOI: 10.1016/j.micpath.2020.104681
Bovine leukemia is a chronic, progressive, contagious tumor disease characterized by malignant lymphoid cell hyperplasia and systemic lymphadenopathy, and is caused by bovine leukemia virus (BLV). The disease affects almost all countries and regions where livestock are raised, and may even be a potential zoonotic disease. Monitoring and early prevention of bovine leukemia is very important. Therefore, we conducted this meta-analysis, the first of its type in the country, to estimate the prevalence of bovine leukemia in 1983-2019 in China. We included a total of 35 publications reported in 1983-2019 from the PubMed, ScienceDirect, Chinese Web of Knowledge (CNKI), VIP Chinese, and Wan Fang databases. In those articles, a total of 34,954 cattle had been tested, of which 4701 were positive for BLV infection. The estimated pooled BLV prevalence was 10.0% (4701/34,954). Subgroup analysis showed that there were significant differences for sampling years, detection methods, and age. BLV prevalence was highest in the following subgroups: sampled before 1985 (38.5%, 437/1134), age 3-5 years (22.5%, 231/1044), and detected by PCR (17.9%, 1228/5100). Regarding geographic factors, there were significant differences in the latitude and elevation subgroups. BLV prevalence was lowest in the subgroups of 20-30 degrees latitude (3.3%, 255/5069) 200-1000 m altitude (2.2%, 560/11,990). We also analyzed other subgroups such as region, variety, breeding method, precipitation, humidity, and temperature, however, the differences were not significant. Our research indicated that the BLV was still prevalent in some of areas in China. We recommend strengthening the testing of cattle aged \textgreater1 year and using flexible testing methods such as PCR to control the prevalence of bovine leukemia and to prevent persistent infection.
Ma, B. Y., Gong, Q. L., Sheng, C. Y., Liu, Y., Ge, G. Y., Li, D. L., Diao, N. C., Shi, K., Li, J. M., Sun, Z. B., Zong, Y., Leng, X., & Du, R. (2021). Prevalence of bovine leukemia in 1983-2019 in China: a systematic review and meta-analysis. Microbial Pathogenesis, 150, 150. https://doi.org/10.1016/j.micpath.2020.104681 China, cattle, Diagnosis of Animal Diseases [LL886], meta-analysis, methodology, methods, systematic reviews, Mathematics and Statistics [ZZ100], Non-communicable Diseases and Injuries of Animals [LL860], data analysis, disease prevalence, epidemiology, zoonoses, zoonotic infections, environmental factors, publications, temperature, domestic animals, livestock, risk factors, viral diseases, diagnosis, monitoring, animal diseases, detection, databases, neoplasms, data banks, prevention, Bovine leukemia virus, viruses, incidence, cancers, PCR, altitude, People’s Republic of China, Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821], viral infections, humidity, hyperplasia, polymerase chain reaction, malignant course, adult bovine lymphosarcoma, adult lymphosarcoma, blood cancer, Bovine leukaemia virus, bovine leukosis, bovine lymphosarcoma, disease incidence, EBL, enzootic bovine leukosis, leucaemia, leukaemia, leukemia, lymphadenopathy, test procedure