VetSRev
Database of veterinary systematic reviews
Database of veterinary systematic reviews
Rev Chilena Infectol (2020) 37: 541–549
DOI: 10.4067/s0716-10182020000500541
BACKGROUND: The evidence regarding genotypic characteristics of Echinococcus granulosus infection in humans worldwide is scarce. AIM: To develop a synthesis of the available evidence regarding genotypes of E. granulosus verified in humans worldwide. METHODS: Systematic review. Articles related with genotypes of E. granulosus, in humans, without language neither genotyped method restriction, published between 1990-2019 were included. A systematic in WoS, EMBASE, MEDLINE, SCOPUS, Trip Database, BIREME, SciELO, LILACS, IBECS, and PAHO-WHO was carried out. In study variables were year of publication, country, number of samples, host and parasite organs, genotype identified, molecular marker and genes. Descriptive statistics were applied. RESULTS: 701 related articles were identified; 62 fulfilled selection criteria, representing 1,511 samples. The existing evidence was published between 1994 and 2019; and mainly comes from Iran (45.2%). The most commonly used sequencing method was PCR amplification and Sanger type sequencing with partial or total genotyping of the cox1 gene. Genotyped method most frequently used was cox1 (79,0%). Genotypes most frequently identified were G1 and G1/G3 complex (49.1% and 32.2%). CONCLUSIONS: Publications related to genotypes of Eg in humans are scarce, heterogeneous, and presenting differing results. Eg G1/G3 accounts for most of the global burden worldwide.
Manterola, C., Rojas, C., Totomoch-Serra, A., García-Méndez, N., & Riffo-Campos Á, L. (2020). [Echinococcus granulosus genotypes verified in human hydatid disease around the world. Systematic review]. Rev Chilena Infectol, 37(5), 541–549. https://doi.org/10.4067/s0716-10182020000500541 Animals, Humans, Genotype, Phylogeny, Polymerase Chain Reaction, *Echinococcosis, *Echinococcus granulosus/genetics