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Mastitis vaccination in dairy cattle: a meta-analysis of field case-control trials

Mata, F

Revista Portuguesa de Ciencias Veterinarias (2013) 108: 17–22

Link: http://www.fmv.utl.pt/spcv/PDF/pdf12_2013/17-22.pdf

Abstract

Mastitis is the first cause of economic loss in the dairy sector. The efficacy of the existing vaccines against mastitis is questioned by several authors. It is the aim of this paper to shed some light on this question. A meta-analysis was conducted on 15 field research trials, which included a total of 7941 cows (4317 vaccinated and 3624 used as control). A random-effects model was adjusted and found significant (P\textless0,01). The unit used was the rate ratio between vaccinated cows and controls and was found to have a value of 0,604 with a 95% confidence interval of [0,373; 0,979], after correction for publication bias. It was concluded that vaccination to control mastitis has a slight advantage, but the economics of its use depends on the weighting between its cost and its benefit, and therefore traditional preventive measures still have an important role to play; Mastitis vaccines can be used as a complement of all the other preventive measures but not as a substitute of these.

Citation

Mata, F. (2013). Mastitis vaccination in dairy cattle: a meta-analysis of field case-control trials. Revista Portuguesa De Ciencias Veterinarias, 108(585/586), 17–22. http://www.fmv.utl.pt/spcv/PDF/pdf12_2013/17-22.pdf [Indexed using CAB Thesaurus terms], animals, Artiodactyla, Chordata, eukaryotes, mammals, ungulates, vertebrates, Animal Immunology [LL650], Bacterial and Fungal Pathogens of Animals [LL821], Bos, Bovidae, bovine mastitis, cattle, cows, dairy Animals [LL110], dairy cattle, dairy cows, Diagnosis of Animal Diseases [LL886], disease control, disease prevention, Host Resistance and Immunity [HH600], mammary glands, meta-analysis, Prion, ruminants, vaccination, vaccines, Viral

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