The global prevalence and risk factors of Cryptosporidium infection among cats during 1988-2021: a systematic review and meta-analysis

Meng, XiangZhu and Li, ManYao and Lyu, Chuang and Qin, YiFeng and Zhao, ZiYu and Yang, XinBo and Ma, Ning and Zhang, Yuan and Zhao, Quan

Microbial Pathogenesis (2021) 158:

DOI: 10.1016/j.micpath.2021.105096

Abstract

Cryptosporidiosis is an important zoonosis caused by Cryptosporidium. This disease causes a global public health problem. The cat is considered to be one of the potential hosts for transmitting Cryptosporidium to humans. In this study, a global meta-analysis for Cryptosporidium infection in cats was performed. The articles related to Cryptosporidium infection in cats were systematically searched in databases China National Knowledge Infrastructure (CNKI), Wanfang data, VIP Chinese Journal Database, PubMed, and ScienceDirect. Finally, 92 articles published from 1988 to 2021, which met the criteria of systematic review and meta-analysis, were collected. During the selected period, the overall prevalence of Cryptosporidium among cats was identified to be 6.0%. The prevalence of Cryptosporidium detected by microscopy, coproantigens, and molecular biology methods were 4.2%, 8.2%, and 5.0%, respectively. Among 9 species/genotypes (C. felis, C. parvum, C. muris, Cryptosporidium rat genotype IV, C. baileyi, C. ryanae, C. hominis, Cryptosporidium sp. rat genotype III and most closely related to Cryptosporidium sp. rat genotype III), the prevalence of C. parvum (4.2%) was significantly higher than that of other species/genotypes. Among five continents, the prevalence of Cryptosporidium in Africa (30.5%) was significantly higher than in other continents. We also analyzed the effects of different geographical factors (longitude, latitude, altitude, mean temperature, precipitation, and humidity) on Cryptosporidium infection among cats. The results showed that cryptosporidiosis was common in cats all over the world. This systematic review and meta-analysis has systematically introduced the global epidemiology of Cryptosporidium in cats and correlated risk factors. Health authorities, doctors, veterinarians and cat owners’ awareness of the prevalence, risk factors and complications of Cryptosporidium are important for the development of effective prevention strategies for cryptosporidiosis.

Citation

Meng, X. Z., Li, M. Y., Lyu, C., Qin, Y. F., Zhao, Z. Y., Yang, X. B., Ma, N., Zhang, Y., & Zhao, Q. (2021). The global prevalence and risk factors of Cryptosporidium infection among cats during 1988-2021: a systematic review and meta-analysis. Microbial Pathogenesis, 158(154). https://doi.org/10.1016/j.micpath.2021.105096 animals, meta-analysis, man, systematic reviews, cats, Pets and Companion Animals [LL070], disease prevalence, epidemiology, public health, zoonoses, zoonotic infections, complications, infections, parasites, parasitoses, protozoal infections, risk factors, animal diseases, Cryptosporidium, cryptosporidiosis, Protozoa, protozoal diseases, parasitic diseases, parasitic infestations, parasitosis, Protozoan, Helminth, Mollusc and Arthropod Parasites of Animals [LL822], Cryptosporidium parvum, Cryptosporidium baileyi, cat diseases, Cryptosporidium felis, Cryptosporidium hominis, Cryptosporidium muris, Cryptosporidium ryanae, molecular biology

Keywords

• animals
• meta-analysis
• man
• systematic reviews
• cats
• Pets and Companion Animals [LL070]
• disease prevalence
• epidemiology
• public health
• zoonoses
• zoonotic infections
• complications
• infections
• parasites
• parasitoses
• protozoal infections
• risk factors
• animal diseases
• Cryptosporidium
• cryptosporidiosis
• Protozoa
• protozoal diseases
• parasitic diseases
• parasitic infestations
• parasitosis
• Protozoan
• Helminth
• Mollusc and Arthropod Parasites of Animals [LL822]
• Cryptosporidium parvum
• Cryptosporidium baileyi
• cat diseases
• Cryptosporidium felis
• Cryptosporidium hominis
• Cryptosporidium muris
• Cryptosporidium ryanae
• molecular biology