Antimicrobial use and resistance in agriculture and food production systems in Africa: a systematic review

Mshana, S. E. and Sindato, C. and Matee, M. I. and Mboera, L. E. G.

Antibiotics (2021) 10:

DOI: 10.3390/antibiotics10080976

Abstract

In Africa, there is dearth of information on antimicrobial use (AMU) in agriculture and food production systems and its consequential resistance in pathogens that affect animal, human and environmental health. Data published between 1980 and 2021 on the magnitude of AMU and AMR in agriculture and food productions systems in Africa were reviewed. Data from 13-27 countries in Africa indicate that 3558-4279 tonnes of antimicrobials were used in animals from 2015 to 2019. Tetracyclines and polypeptides contributed the largest proportion of antimicrobials used. Cattle and poultry production account for the largest consumption of antimicrobials in Africa. Although limited studies have reported AMR in crops, fish and beekeeping, AMR from a variety of farm animals has been substantially documented in Africa. Some countries in Africa have developed policies/plans to address AMU and AMR in agriculture and food production systems; however, their enforcement is challenged by weak regulations. In conclusion, although there is limited information on the quantities of antimicrobials used in agriculture and food production system, the levels of AMR are high. There is a need to strengthen regulatory authorities with a capacity to monitor AMU in agriculture and food production systems in Africa.

Citation

Mshana, S. E., Sindato, C., Matee, M. I., & Mboera, L. E. G. (2021). Antimicrobial use and resistance in agriculture and food production systems in Africa: a systematic review. Antibiotics, 10(8). https://doi.org/10.3390/antibiotics10080976 cattle, man, systematic reviews, Africa, drug resistance, food safety, Pesticide and Drug Resistance [HH410], public health, birds, domesticated birds, poultry, domestic animals, livestock, agriculture, pathogens, environmental health, tetracyclines, Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821], Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210], antiinfective agents, antimicrobials, Food Contamination, Residues and Toxicology [QQ200], food production

Keywords

• cattle
• man
• systematic reviews
• Africa
• drug resistance
• food safety
• Pesticide and Drug Resistance [HH410]
• public health
• birds
• domesticated birds
• poultry
• domestic animals
• livestock
• agriculture
• pathogens
• environmental health
• tetracyclines
• Prion
• Viral
• Bacterial and Fungal Pathogens of Animals [LL821]
• Prion
• Viral
• Bacterial and Fungal Pathogens of Humans [VV210]
• antiinfective agents
• antimicrobials
• Food Contamination
• Residues and Toxicology [QQ200]
• food production