Effects of fatty and lean fish intake on stroke risk: a meta-analysis of prospective cohort studies

Qin, Z. Z. and Xu, J. Y. and Chen, G. C. and Ma, Y. X. and Qin, L. Q.

Lipids Health Dis (2018) 17: 264

DOI: 10.1186/s12944-018-0897-z

Abstract

BACKGROUND: Fish intake has been postulated to reduce the risk of stroke. However, whether the beneficial effect of fish are mainly linked to fat content, as a source of omega-3 polyunsaturated fatty acids, remains unclear. We conducted a meta-analysis to compare the effect of fatty and lean fish intake on stroke risk. METHODS: We performed a literature search on four database (PubMed, Embase, Scopus, and Cochrane Library) through February 1, 2018 to identify prospective studies of fatty and lean fish in relation to stroke risk. A random-effects model was used to calculate the summary estimates. RESULTS: We identified five prospective studies, including 7 comparisons for fatty fish intake and 5 comparisons for lean fish intake. Compared with the highest category of intake with lowest category, the summary relative risk was 0.88 [95% confidence interval (CI), 0.74-1.04] for fatty fish intake and 0.81 (95% CI, 0.67-0.99) for lean fish intake. No heterogeneity across studies and publication bias were observed. CONCLUSION: Our findings demonstrated that fatty and lean fish intake has beneficial effects on stroke risk, especially lean fish intake. Additional prospective studies are necessary to confirm these observations.

Citation

Qin, Z. Z., Xu, J. Y., Chen, G. C., Ma, Y. X., & Qin, L. Q. (2018). Effects of fatty and lean fish intake on stroke risk: a meta-analysis of prospective cohort studies. Lipids Health Dis, 17(1), 264. https://doi.org/10.1186/s12944-018-0897-z Animals, Humans, Risk Factors, Prospective Studies, Meta-analysis, *Fishes, Seafood, Stroke/*epidemiology, authors declare that they have no competing interest. PUBLISHER’S NOTE: Springer, Fatty Acids, Omega-3, Fatty fish, institutional affiliations., Lean fish, Nature remains neutral with regard to jurisdictional claims in published maps and, Not applicable. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The, Stroke risk

Keywords

• Animals
• Humans
• Risk Factors
• Prospective Studies
• Meta-analysis
• *Fishes
• Seafood
• Stroke/*epidemiology
• authors declare that they have no competing interest. PUBLISHER’S NOTE: Springer
• Fatty Acids
• Omega-3
• Fatty fish
• institutional affiliations.
• Lean fish
• Nature remains neutral with regard to jurisdictional claims in published maps and
• Not applicable. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The
• Stroke risk