The global prevalence of Cryptosporidium infection in dogs: A systematic review and meta-analysis

Taghipour, A. and Olfatifar, M. and Bahadory, S. and Godfrey, S. S. and Abdoli, A. and Khatami, A. and Javanmard, E. and Shahrivar, F.

Vet Parasitol (2020) 281: 109093

DOI: 10.1016/j.vetpar.2020.109093

Abstract

Cryptosporidiosis, caused by the protozoan parasite Cryptosporidium spp., is an important zoonotic disease and is considered a global public health concern. Dogs are suggested as one of potential reservoirs for transmitting the Cryptosporidium infection to humans. However, there is a paucity of information about global patterns of occurrence of Cryptosporidium in dogs. A systematic review and meta-analysis were carried out to evaluate the global prevalence of Cryptosporidium infection among dogs. In this study, PubMed, Scopus, Web of Science and Google Scholar databases were systematically searched for relevant studies up until October 30, 2019. Finally, 127 articles (including 160 datasets) were eligible for inclusion in the systematic review and meta-analysis. The overall prevalence of Cryptosporidium infection was estimated at 8% (95 % CI: 5-11 %) using microscopic methods, 7% (95 % CI: 4-10%) using coprogantigenic methods and 6% (95 % CI: 4-9%) using molecular diagnostic methods. Molecular methods revealed that dogs were most frequently infected by C. canis (3.64 %) and C. parvum (1.28 %). The pooled prevalence different of subgroups (WHO regions, geographic and climate parameters, diagnostic methods, type of dog) were analyzed separately. The pooled odds ratio (OR) of Cryptosporidium was significantly higher than one for diarrhea status, with dogs suffering from diarrhea having a higher likelihood of Cryptosporidium infection, compared to dogs without diarrhea (OR; 3.61 95 % CI: 1.89-6.90%). The present study is the first systematic review and meta-analysis providing a comprehensive view of the global prevalence of Cryptosporidium in dogs and its related risk factors. Awareness of Cryptosporidium prevalence, risk factors, and disease complications for the health authorities, physicians, veterinarians and dog’s owners is important for developing effective strategies to prevent infection.

Citation

Taghipour, A., Olfatifar, M., Bahadory, S., Godfrey, S. S., Abdoli, A., Khatami, A., Javanmard, E., & Shahrivar, F. (2020). The global prevalence of Cryptosporidium infection in dogs: A systematic review and meta-analysis. Vet Parasitol, 281, 109093. https://doi.org/10.1016/j.vetpar.2020.109093 Animals, Dogs, Risk Factors, Global Health, Prevalence, Cryptosporidium/physiology, Meta-analysis, Cryptosporidium, competing financial interests or personal relationships that could have appeared to, influence the work reported in this paper., Cryptosporidiosis/complications/*parasitology/prevention & control, Diarrhea/etiology, Dog Diseases/*parasitology/prevention & control

Keywords

• Animals
• Dogs
• Risk Factors
• Global Health
• Prevalence
• Cryptosporidium/physiology
• Meta-analysis
• Cryptosporidium
• competing financial interests or personal relationships that could have appeared to
• influence the work reported in this paper.
• Cryptosporidiosis/complications/*parasitology/prevention & control
• Diarrhea/etiology
• Dog Diseases/*parasitology/prevention & control