The global prevalence of highly pathogenic avian influenza A (H5N8) infection in birds: A systematic review and meta-analysis.

Yang XY and Gong QL and Li YJ and Emad BA and Hu MJ and Sun YY and Xue ZY and Yang YS and Sun XP and Shi CW and Yang GL and Huang HB and Jiang YL and Wang JZ and Cao X and Wang N and Zeng Y and Yang WT and Wang CF

Microbial pathogenesis (2023) : 106001

DOI: 10.1016/j.micpath.2023.106001

Abstract

The zoonotic pathogen avian influenza A H5N8 causes enormous economic losses in the poultry industry and poses a serious threat to the public health. Here, we report the first systematic review and meta-analysis of the worldwide prevalence of birds. We filtered 45 eligible articles from seven databases. A random-effects model was used to analyze the prevalence of H5N8 in birds. The pooled prevalence of H5N8 in birds was 1.6%. In the regions, Africa has the highest prevalence (8.0%). Based on the source, village (8.3%) was the highest. In the sample type, the highest prevalence was organs (79.7%). In seasons, the highest prevalence was autumn (28.1%). The largest prevalence in the sampling time was during 2019 or later (7.0%). Furthermore, geographical factors also were associated with the prevalence. Therefore, we recommend site-specific prevention and control tools for this strain in birds and enhance the surveillance to reduce the spread of H5N8.

Citation

Yang XY, Gong QL, Li YJ, Emad BA, Hu MJ, Sun YY, Xue ZY, Yang YS, Sun XP, Shi CW, Yang GL, Huang HB, Jiang YL, Wang JZ, Cao X, Wang N, Zeng Y, Yang WT, & Wang CF. (2023). The global prevalence of highly pathogenic avian influenza A (H5N8) infection in birds: A systematic review and meta-analysis. Microbial Pathogenesis, 106001. https://doi.org/10.1016/j.micpath.2023.106001 Prevalence, Influenza, Human

Keywords

• Prevalence
• Influenza
• Human